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Single neuron responses to auditory and visual cues during three different variations of a Multi-modal center-out iBCI task. ( A – C ) Task sequences for three variants of a Multi-modal center-out task consisting of different cue presentation orders: auditory-visual (AV) task sequence ( A ), visual-auditory (VA) task sequence ( B ), and the simultaneous cue (A + V) presentation sequence ( C ). ( D – F ) Example raster-histograms for a single MFG neuron ( top row, yellow banner ) and PCG neuron ( bottom row, teal banner ) during the AV task sequence ( D ), the VA task sequence ( E ), and the A + V task sequence ( F ). Averaged firing rate traces for each target (smoothed with a 200 ms Gaussian kernel) are presented under each raster plot. White triangles (∇) represent the instructional cue onsets; black triangles represent the go cue onset; Ear symbol represents an auditory cue; eye symbol represents a visual cue (trial day 356, MFG channel 17, unit 1, PCG channel 12, unit 3). ( G – I ) Percentages of MFG ( yellow line s) and PCG neurons ( teal lines ) with responsive ( broken line ) and selective ( solid line ) firing patterns during the AV ( G ), the VA ( H ), and the A + V ( I ) task sequence. Neurons were classified as responsive if they displayed firing rates significantly different from baseline during task performance (significance level = 0.01; Kruskal–Wallis (KW) test), and selective if firing rates differed significantly across targets. This figure was compiled using MATLAB <t>2017b,</t> MathWorks software and labeled using Adobe Illustrator CC 2018.
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Single neuron responses to auditory and visual cues during three different variations of a Multi-modal center-out iBCI task. ( A – C ) Task sequences for three variants of a Multi-modal center-out task consisting of different cue presentation orders: auditory-visual (AV) task sequence ( A ), visual-auditory (VA) task sequence ( B ), and the simultaneous cue (A + V) presentation sequence ( C ). ( D – F ) Example raster-histograms for a single MFG neuron ( top row, yellow banner ) and PCG neuron ( bottom row, teal banner ) during the AV task sequence ( D ), the VA task sequence ( E ), and the A + V task sequence ( F ). Averaged firing rate traces for each target (smoothed with a 200 ms Gaussian kernel) are presented under each raster plot. White triangles (∇) represent the instructional cue onsets; black triangles represent the go cue onset; Ear symbol represents an auditory cue; eye symbol represents a visual cue (trial day 356, MFG channel 17, unit 1, PCG channel 12, unit 3). ( G – I ) Percentages of MFG ( yellow line s) and PCG neurons ( teal lines ) with responsive ( broken line ) and selective ( solid line ) firing patterns during the AV ( G ), the VA ( H ), and the A + V ( I ) task sequence. Neurons were classified as responsive if they displayed firing rates significantly different from baseline during task performance (significance level = 0.01; Kruskal–Wallis (KW) test), and selective if firing rates differed significantly across targets. This figure was compiled using MATLAB <t>2017b,</t> MathWorks software and labeled using Adobe Illustrator CC 2018.
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Single neuron responses to auditory and visual cues during three different variations of a Multi-modal center-out iBCI task. ( A – C ) Task sequences for three variants of a Multi-modal center-out task consisting of different cue presentation orders: auditory-visual (AV) task sequence ( A ), visual-auditory (VA) task sequence ( B ), and the simultaneous cue (A + V) presentation sequence ( C ). ( D – F ) Example raster-histograms for a single MFG neuron ( top row, yellow banner ) and PCG neuron ( bottom row, teal banner ) during the AV task sequence ( D ), the VA task sequence ( E ), and the A + V task sequence ( F ). Averaged firing rate traces for each target (smoothed with a 200 ms Gaussian kernel) are presented under each raster plot. White triangles (∇) represent the instructional cue onsets; black triangles represent the go cue onset; Ear symbol represents an auditory cue; eye symbol represents a visual cue (trial day 356, MFG channel 17, unit 1, PCG channel 12, unit 3). ( G – I ) Percentages of MFG ( yellow line s) and PCG neurons ( teal lines ) with responsive ( broken line ) and selective ( solid line ) firing patterns during the AV ( G ), the VA ( H ), and the A + V ( I ) task sequence. Neurons were classified as responsive if they displayed firing rates significantly different from baseline during task performance (significance level = 0.01; Kruskal–Wallis (KW) test), and selective if firing rates differed significantly across targets. This figure was compiled using MATLAB <t>2017b,</t> MathWorks software and labeled using Adobe Illustrator CC 2018.
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Single neuron responses to auditory and visual cues during three different variations of a Multi-modal center-out iBCI task. ( A – C ) Task sequences for three variants of a Multi-modal center-out task consisting of different cue presentation orders: auditory-visual (AV) task sequence ( A ), visual-auditory (VA) task sequence ( B ), and the simultaneous cue (A + V) presentation sequence ( C ). ( D – F ) Example raster-histograms for a single MFG neuron ( top row, yellow banner ) and PCG neuron ( bottom row, teal banner ) during the AV task sequence ( D ), the VA task sequence ( E ), and the A + V task sequence ( F ). Averaged firing rate traces for each target (smoothed with a 200 ms Gaussian kernel) are presented under each raster plot. White triangles (∇) represent the instructional cue onsets; black triangles represent the go cue onset; Ear symbol represents an auditory cue; eye symbol represents a visual cue (trial day 356, MFG channel 17, unit 1, PCG channel 12, unit 3). ( G – I ) Percentages of MFG ( yellow line s) and PCG neurons ( teal lines ) with responsive ( broken line ) and selective ( solid line ) firing patterns during the AV ( G ), the VA ( H ), and the A + V ( I ) task sequence. Neurons were classified as responsive if they displayed firing rates significantly different from baseline during task performance (significance level = 0.01; Kruskal–Wallis (KW) test), and selective if firing rates differed significantly across targets. This figure was compiled using MATLAB <t>2017b,</t> MathWorks software and labeled using Adobe Illustrator CC 2018.
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Single neuron responses to auditory and visual cues during three different variations of a Multi-modal center-out iBCI task. ( A – C ) Task sequences for three variants of a Multi-modal center-out task consisting of different cue presentation orders: auditory-visual (AV) task sequence ( A ), visual-auditory (VA) task sequence ( B ), and the simultaneous cue (A + V) presentation sequence ( C ). ( D – F ) Example raster-histograms for a single MFG neuron ( top row, yellow banner ) and PCG neuron ( bottom row, teal banner ) during the AV task sequence ( D ), the VA task sequence ( E ), and the A + V task sequence ( F ). Averaged firing rate traces for each target (smoothed with a 200 ms Gaussian kernel) are presented under each raster plot. White triangles (∇) represent the instructional cue onsets; black triangles represent the go cue onset; Ear symbol represents an auditory cue; eye symbol represents a visual cue (trial day 356, MFG channel 17, unit 1, PCG channel 12, unit 3). ( G – I ) Percentages of MFG ( yellow line s) and PCG neurons ( teal lines ) with responsive ( broken line ) and selective ( solid line ) firing patterns during the AV ( G ), the VA ( H ), and the A + V ( I ) task sequence. Neurons were classified as responsive if they displayed firing rates significantly different from baseline during task performance (significance level = 0.01; Kruskal–Wallis (KW) test), and selective if firing rates differed significantly across targets. This figure was compiled using MATLAB <t>2017b,</t> MathWorks software and labeled using Adobe Illustrator CC 2018.
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Single neuron responses to auditory and visual cues during three different variations of a Multi-modal center-out iBCI task. ( A – C ) Task sequences for three variants of a Multi-modal center-out task consisting of different cue presentation orders: auditory-visual (AV) task sequence ( A ), visual-auditory (VA) task sequence ( B ), and the simultaneous cue (A + V) presentation sequence ( C ). ( D – F ) Example raster-histograms for a single MFG neuron ( top row, yellow banner ) and PCG neuron ( bottom row, teal banner ) during the AV task sequence ( D ), the VA task sequence ( E ), and the A + V task sequence ( F ). Averaged firing rate traces for each target (smoothed with a 200 ms Gaussian kernel) are presented under each raster plot. White triangles (∇) represent the instructional cue onsets; black triangles represent the go cue onset; Ear symbol represents an auditory cue; eye symbol represents a visual cue (trial day 356, MFG channel 17, unit 1, PCG channel 12, unit 3). ( G – I ) Percentages of MFG ( yellow line s) and PCG neurons ( teal lines ) with responsive ( broken line ) and selective ( solid line ) firing patterns during the AV ( G ), the VA ( H ), and the A + V ( I ) task sequence. Neurons were classified as responsive if they displayed firing rates significantly different from baseline during task performance (significance level = 0.01; Kruskal–Wallis (KW) test), and selective if firing rates differed significantly across targets. This figure was compiled using MATLAB <t>2017b,</t> MathWorks software and labeled using Adobe Illustrator CC 2018.
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Single neuron responses to auditory and visual cues during three different variations of a Multi-modal center-out iBCI task. ( A – C ) Task sequences for three variants of a Multi-modal center-out task consisting of different cue presentation orders: auditory-visual (AV) task sequence ( A ), visual-auditory (VA) task sequence ( B ), and the simultaneous cue (A + V) presentation sequence ( C ). ( D – F ) Example raster-histograms for a single MFG neuron ( top row, yellow banner ) and PCG neuron ( bottom row, teal banner ) during the AV task sequence ( D ), the VA task sequence ( E ), and the A + V task sequence ( F ). Averaged firing rate traces for each target (smoothed with a 200 ms Gaussian kernel) are presented under each raster plot. White triangles (∇) represent the instructional cue onsets; black triangles represent the go cue onset; Ear symbol represents an auditory cue; eye symbol represents a visual cue (trial day 356, MFG channel 17, unit 1, PCG channel 12, unit 3). ( G – I ) Percentages of MFG ( yellow line s) and PCG neurons ( teal lines ) with responsive ( broken line ) and selective ( solid line ) firing patterns during the AV ( G ), the VA ( H ), and the A + V ( I ) task sequence. Neurons were classified as responsive if they displayed firing rates significantly different from baseline during task performance (significance level = 0.01; Kruskal–Wallis (KW) test), and selective if firing rates differed significantly across targets. This figure was compiled using MATLAB <t>2017b,</t> MathWorks software and labeled using Adobe Illustrator CC 2018.
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Image Search Results


Single neuron responses to auditory and visual cues during three different variations of a Multi-modal center-out iBCI task. ( A – C ) Task sequences for three variants of a Multi-modal center-out task consisting of different cue presentation orders: auditory-visual (AV) task sequence ( A ), visual-auditory (VA) task sequence ( B ), and the simultaneous cue (A + V) presentation sequence ( C ). ( D – F ) Example raster-histograms for a single MFG neuron ( top row, yellow banner ) and PCG neuron ( bottom row, teal banner ) during the AV task sequence ( D ), the VA task sequence ( E ), and the A + V task sequence ( F ). Averaged firing rate traces for each target (smoothed with a 200 ms Gaussian kernel) are presented under each raster plot. White triangles (∇) represent the instructional cue onsets; black triangles represent the go cue onset; Ear symbol represents an auditory cue; eye symbol represents a visual cue (trial day 356, MFG channel 17, unit 1, PCG channel 12, unit 3). ( G – I ) Percentages of MFG ( yellow line s) and PCG neurons ( teal lines ) with responsive ( broken line ) and selective ( solid line ) firing patterns during the AV ( G ), the VA ( H ), and the A + V ( I ) task sequence. Neurons were classified as responsive if they displayed firing rates significantly different from baseline during task performance (significance level = 0.01; Kruskal–Wallis (KW) test), and selective if firing rates differed significantly across targets. This figure was compiled using MATLAB 2017b, MathWorks software and labeled using Adobe Illustrator CC 2018.

Journal: Scientific Reports

Article Title: Auditory cues reveal intended movement information in middle frontal gyrus neuronal ensemble activity of a person with tetraplegia

doi: 10.1038/s41598-020-77616-8

Figure Lengend Snippet: Single neuron responses to auditory and visual cues during three different variations of a Multi-modal center-out iBCI task. ( A – C ) Task sequences for three variants of a Multi-modal center-out task consisting of different cue presentation orders: auditory-visual (AV) task sequence ( A ), visual-auditory (VA) task sequence ( B ), and the simultaneous cue (A + V) presentation sequence ( C ). ( D – F ) Example raster-histograms for a single MFG neuron ( top row, yellow banner ) and PCG neuron ( bottom row, teal banner ) during the AV task sequence ( D ), the VA task sequence ( E ), and the A + V task sequence ( F ). Averaged firing rate traces for each target (smoothed with a 200 ms Gaussian kernel) are presented under each raster plot. White triangles (∇) represent the instructional cue onsets; black triangles represent the go cue onset; Ear symbol represents an auditory cue; eye symbol represents a visual cue (trial day 356, MFG channel 17, unit 1, PCG channel 12, unit 3). ( G – I ) Percentages of MFG ( yellow line s) and PCG neurons ( teal lines ) with responsive ( broken line ) and selective ( solid line ) firing patterns during the AV ( G ), the VA ( H ), and the A + V ( I ) task sequence. Neurons were classified as responsive if they displayed firing rates significantly different from baseline during task performance (significance level = 0.01; Kruskal–Wallis (KW) test), and selective if firing rates differed significantly across targets. This figure was compiled using MATLAB 2017b, MathWorks software and labeled using Adobe Illustrator CC 2018.

Article Snippet: This figure was compiled using MATLAB 2017b, MathWorks software and labeled using Adobe Illustrator CC 2018.

Techniques: Sequencing, Software, Labeling